The content of this page is not yet available in English.

Georges Pelletier

Centre de recherche en endocrinologie moléculaire et oncologique et génomique humaine (CREMOGH)
Axe endocrinologie et génomique du CRCHUQ
Adresse
2705, boulevard Laurier, T-3-67
Québec (Québec)
CANADA G1V 4G2
Téléphone
+1 418-525-4444 poste 42296
Télécopieur
+1 418-654-2761
Courriel
Georges.Pelletier@crchul.ulaval.ca
Expression des enzymes impliqués dans la biosynthèse et le métabolisme des estrogènes et des androgènes dans les cancers hormono-dépendants.

Rôle et mécanismes d’action des endozépines dans le contrôle de la prise alimentaire.

Publications récentes

Li Z, Luu-The V, Poisson-Pare D, Ouellet J, Li S, Labrie F, Pelletier G. Expression of enzymes involved in synthesis and metabolism of estradiol in human breast as studied by immunocytochemistry and in situ hybridization. Histology and histopathology,  2009. 24: 273-82
Han B, Li S, Song D, Poisson-Pare D, Liu G, Luu-The V, Ouellet J, Labrie F, Pelletier G. Expression of 17beta-hydroxysteroid dehydrogenase type 2 and type 5 in breast cancer and adjacent non-malignant tissue: A correlation to clinicopathological parameters. The Journal of steroid biochemistry and molecular biology,  2008. 112: 194-200
Kaeding J, Bouchaert E, Belanger J, Caron P, Chouinard S, Verreault M, Larouche O, Pelletier G, Staels B, Belanger A, Barbier O. Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells. The Biochemical journal,  2008. 410: 245-53
Ivanga M, Labrie Y, Calvo E, Belleau P, Martel C, Pelletier G, Morissette J, Labrie F, Durocher F. Fine temporal analysis of DHT transcriptional modulation of the ATM/Gadd45g signaling pathways in the mouse uterus. Molecular reproduction and development,  2008. Epub
Sakurai N, Maruo K, Haraguchi S, Uno Y, Oshima Y, Tsutsui K, Matsuda Y, Rego JL, Pelletier G, Vaudry H, Nakamura M. Immunohistochemical detection and biological activities of CYP17 (P450c17) in the indifferent gonad of the frog Rana rugosa. The Journal of steroid biochemistry and molecular biology,  2008. Epub
Pelletier G, Labrie C, Martel C, Labrie F. Chronic administration of dehydroepiandrosterone (DHEA) to female monkey and rat has no effect on mammary gland histology. The Journal of steroid biochemistry and molecular biology,  2008. 108: 102-8
Chouinard S, Yueh MF, Tukey RH, Giton F, Fiet J, Pelletier G, Barbier O, Belanger A. Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling. The Journal of steroid biochemistry and molecular biology,  2008. 109: 247-53
Pelletier G. Expression of steroidogenic enzymes and sex-steroid receptors in human prostate. Best practice & research. Clinical endocrinology & metabolism,  2008. 22: 223-8
Do Rego JL, Leprince J, Luu-The V, Pelletier G, Tonon MC, Vaudry H. Structure-activity relationships of a series of analogs of the endozepine octadecaneuropeptide (ODN(11)(-)(18)) on neurosteroid biosynthesis by hypothalamic explants. Journal of medicinal chemistry,  2007. 50: 3070-6
Pelletier G, Li S, Luu-The V, Labrie F. Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. Journal of neuroendocrinology,  2007. 19: 426-31