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Olivier Barbier

Centre de recherche en endocrinologie moléculaire et oncologique et génomique humaine (CREMOGH)
Axe endocrinologie et génomique du CRCHUQ
Adresse
2705, boulevard Laurier, T-3-67
Québec (Québec)
CANADA G1V 4G2
Téléphone
+1 418-525-4444 poste 42296
Télécopieur
+1 418-654-2761
Courriel
Olivier.Barbier@pha.ulaval.ca
 

Projets de recherche actifs

Aucun projet de recherche à afficher

Publications récentes

Barbier O, Trottier J, Kaeding J, Caron P, Verreault M. Lipid-activated transcription factors control bile acid glucuronidation. Molecular and cellular biochemistry,  2009. Epub
Kaeding J, Bouchaert E, Belanger J, Caron P, Chouinard S, Verreault M, Larouche O, Pelletier G, Staels B, Belanger A, Barbier O. Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells. The Biochemical journal,  2008. 410: 245-53
Barbier O, Belanger A. Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate. Best practice & research. Clinical endocrinology & metabolism,  2008. 22: 259-70
Chouinard S, Yueh MF, Tukey RH, Giton F, Fiet J, Pelletier G, Barbier O, Belanger A. Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling. The Journal of steroid biochemistry and molecular biology,  2008. 109: 247-53
Barbier O. Nuclear receptor-mediated regulation of phase II conjugated enzymes In: Xie W, ed.  Nuclear receptors in drug metabolism Hoboken, NJ: John Wiley & Sons, 2008. p.chapter 3.
Kaeding J, Belanger J, Caron P, Verreault M, Belanger A, Barbier O. Calcitrol (1{alpha},25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells. Molecular cancer therapeutics,  2008. 7: 380-90
Chouinard S, Barbier O, Belanger A. UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells. The Journal of biological chemistry,  2007. 282: 33466-74
Caillier B, Lepine J, Tojcic J, Menard V, Perusse L, Belanger A, Barbier O, Guillemette C. A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3. Pharmacogenetics and genomics,  2007. 17: 481-495
Senekeo-Effenberger K, Chen S, Brace-Sinnokrak E, Bonzo JA, Yueh MF, Argikar U, Kaeding J, Trottier J, Remmel RP, Ritter JK, Barbier O, Tukey RH. Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation. Drug metabolism and disposition: the biological fate of chemicals,  2007. 35: 419-27
Trottier J, Verreault M, Grepper S, Monté D, Bélanger J, Kaeding J, Caron P, Inaba TT, Barbier O. Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver.  Hepatology (Baltimore, Md.) ,  2006. 44: 1158-70