New analytic technology

The bioinformatics platform provides the analysis of genomic and proteomic data from fundamental and clinical research as well as computerization and analysis of the data of the genomics and proteomics platforms.

In collaboration with fundamental and clinical investigators, bioinformatics conceives and applies methods of analysis, programs and informatics tools needed to establish the molecular profiles of messenger RNAs and proteins, for the characterization of new genes, the elucidation of biological gene functions, the identification of therapeutic targets as well as the development of diagnostic and detection tools while supporting population and pharmacogenomic studies. All this information coming from new genomics and proteomics technology opens the door to new approaches and individualized medicine.

Integration of research data

Conception of analysis tools relies on databases and software tools created internally and enabling the merging of new data with the enormous pool of public genomics and proteomics data (genome sequences, protein structures, functional classifications…). Bioinformatics research activities are aimed at the integration of multiple sources of data, genome annotation, gene expression analysis (Affymetrix and oligo-chips, quantitative RT-PCR, EST banks, SAGE), protein identification by mass spectrometry, distributed calculation and semantic web technologies.

Laboratory Information Management Systems (LIMS)

Computerization of the genomics center platforms involves the creation of integrated Laboratory Information Management Systems (LIMS), automated analysis pipelines, experiment planning tools and manager/client interfaces.

Current needs in bioinformatics call for skilled personnel in multiple theoretical and applied areas including engineers, biologists, programmers, statisticians and mathematicians, all working closely with the biological research personnel.